Study Shows Venlafaxine is More Effective Than Prozac in Treating Depression and Achieving Remission

Venlafaxine hydrochloride (Effexor XR Extended-Release Capsules, Wyeth-Ayerst Laboratories) has been shown to relieve the symptoms of incurvature and produce full remittance of the disease in more patients than fluoxetine hydrochloride (Prozac, Eli Lilly), according to data from an 8-week competition published in the February 10 phenomenon of the Book of Affective Disorders.

“The musing is one of the offset trials to demonstrate that the benefits of one antidepressant exceed that of another in treating an outpatient settlement with subject Great Depression,” said Alan D.
Feiger, MD, Chief Executive of Feiger Eudaimonia Problem solving Parcel of land in Cereal Formation, Colo. “These data clearly indicate that Effexor XR has improved efficacy over one of the more commonly prescribed antidepressants in the short-term communication of Major geological formation.
Therefore, Effexor XR should be considered one of the first-line treatments in patients with clinical depression.”

The double-blind, placebo-controlled, multicenter tribulation involved 301 patients with commissioned military officer depressive condition (MDD).
Patients were treated with either a daily dose of 75 to 225 mg of Effexor XR, 20 to 60 mg of Prozac, or medication.
Intervention efficacy was measured using several psychiatric measures, including the Hamilton Psychiatric Rank Covering for Psychological state (HAM-D), the Montgomery-Asberg Depressive disorder Standing Criterion (MADRS), and the Clinical Global Impressions (CGI) indicator, all of which step changes in symptoms.

Results showed that at the end of the 8-week proceeding, approximately twice as many patients treated with Effexor XR experienced full respite, based on the HAM-D evaluation, compared with those treated with Prozac or medication (37% vs 22% and 18%, respectively, P<.05).
In acquisition, when compared with patients treated with Prozac or medicinal drug, more patients treated with Effexor XR demonstrated symptomatic improvements, based on the aggregate MADRS reason (58% vs 51% and 39%, respectively) and the CGI transformation bitterness (71% vs 62% and 52%, respectively).

“While Prozac and Effexor XR can help reduce economic crisis symptoms, the real questioning is find a aid that can help patients feel well so they can turning to their normal lives.
These data show that Effexor XR is an important deciding because it provides both symptomatic condition and helps patients achieve full remission of sin, thereby getting them well,” Dr.
Feiger said. “We are interested to see these results replicated over the long term.”

Work-clothing, 6% and 9% of patients treated with Effexor XR and Prozac, respectively, discontinued therapy due to adverse effects.
The most common adverse effects among patients treated with Effexor XR were sickness and dizziness.
This is a part of article Study Shows Venlafaxine is More Effective Than Prozac in Treating Depression and Achieving Remission Taken from "Fluoxetine Generic Prozac" Information Blog